Diabetes mellitus has long been recognized by the World Health Organization as a very dangerous disease, as several million people die from it every year on the planet. Unfortunately, it is not possible to completely get rid of this disease, but modern medicine has reached such a level of development that it is able to maintain the patient’s state of health in a fairly acceptable form through the use of a variety of medicines.

Over the past few years, the pharmacological industry has made some serious steps in this direction, so the choice of drugs today is quite large. They allow you to keep your sugar levels under control. In our today’s ranking, we would like to tell you as much as possible about the best blood sugar lowering drugs in 2022. In the review, we will talk about the key characteristics of the most popular medicines, give some very important tips on choosing these products. However, in any case, it must be remembered that each medicine has its own contraindications and side effects. You should not try to treat diabetes on your own, so before buying the drug, you should consult with your doctor.

How to choose the right medicine to lower blood sugar?

It must be said right away that in a person who does not suffer from diabetes, the level of sugar in the blood is always at about the same level with slight fluctuations. This factor does not depend on what kind of food a person took and in what quantity. According to medical indicators, the norm is in the range from 2.5 to 8 mmol / l.

If earlier, when medicine had not yet reached a certain level of development, a person with diabetes developed a ketoacidotic comp for a few years, which resulted in a fatal outcome, but today such cases are extremely rare. They can occur in people who do not pay attention to the state of their health at all, do not contact a specialist in a timely manner, or do not follow his recommendations. As a result, the level of sugar can reach critical values, which leads to disastrous consequences.

In addition, diabetes is very dangerous due to various complications. Because of this disease, atherosclerosis is formed, coronary heart disease can develop, various kinds of damage to blood vessels and nerve cells, even limbs can lose their sensitivity. In the most advanced cases, the patient may fail to see, gangrene develop, chronic kidney failure begins, diabetes even leads to heart attacks and strokes. In particular, type 1 diabetes is caused by the death of pancreatic cells — in this case, no medication will help the patient, so the person will have to regularly inject himself with insulin.

Today on sale you can find several varieties of medicines designed to lower blood sugar levels at once. They can act in different ways — stimulate increased production of insulin by the pancreas, reduce the amount of glucose that the liver produces, and so on. When we made the choice of medicines for inclusion in the ranking of the best drugs for lowering blood sugar, we took into account all the factors that were discussed earlier. This includes far from the most expensive funds, so most of our readers will be able to choose the best drugs for themselves without compromising their budget. I would like to express the hope that after a thorough study of the rating and after consultation with your doctor, you will be able to choose the most suitable drug for yourself, which can significantly slow down the progression of diabetes.

Five of the best drugs to lower blood sugar

5. Diabecon

Diabecon photo

This remedy is a unique medicine that includes an Ayurvedic mixture, which consists of 30 herbs and minerals. All of them are selected in optimal concentration, due to which it is possible to provide gentle and safe glycemic control for the patient’s health. All of them contribute to the absorption of glucose, so the sugar level will be kept at a normal level. In addition, the drug will maintain healthy levels of cholesterol and triglycerides, the concentration of which also significantly affects the patient’s health. The tool supports the healthy functioning of the pancreas, provides accelerated regeneration of its cells, supports lipid metabolism. It can be used even by people who have only a suspicion of diabetes mellitus to prevent its further development.

Take the medicine two tablets twice a day half an hour before meals, but the specialist can increase the dosage to a three-time dose of the drug. The form factor is quite acceptable — the diameter of the tablet is 11 mm with a thickness of no more than 2 mm, so it is very easy to swallow them. The most effective active substance in this drug is Guggul, which, in addition to controlling sugar levels, can lower cholesterol and lipids. Additionally, it prevents the destruction of pancreatic cells by stimulating the natural production of insulin. It is a natural antioxidant.


  • Very convenient form factor;
  • Allows you to easily control blood sugar levels and a number of additional vital signs;
  • There are no complications;
  • Produced only from natural compounds and extracts.


  • It is difficult to meet in pharmacies, you have to order exclusively via the Internet — you need to wait a long time for an order.


4. Oligim

Oligim photo

Another drug created on the basis of natural herbal supplements and extracts, however, was developed by domestic pharmacologists from the Evalar company. The substances contained in this drug reduce the degree of absorption of sugars and glucose from food. Thanks to this function, excess sugar simply does not enter the bloodstream and is excreted outside the human body in a natural way. In addition, the drug maintains blood sugar levels within normal limits, stimulates the pancreas, so insulin is produced in sufficient quantities, the cells of all organs remain sensitive to it. Also, this medicine stabilizes the metabolism of fats and carbohydrates, reduces cravings for sweets, affecting the taste buds. If the patient is prescribed a special diet, then it will be much easier for a person to follow it.

The drug is based on the extract of goat’s rue officinalis — it is with its help that blood sugar can be maintained in the normal range. Cowberry leaf extract is characterized by a diuretic effect, so sugars and insoluble salts will be removed from the body much faster. The addition of nettle leaves stimulates the production of insulin at the proper level. The composition also contains 11 vitamins and 8 minerals, which are additionally enhanced with taurine. Due to the fact that the products are completely natural, it can be taken for as long as you like.


  • Consists exclusively of natural preparations;
  • You can take the remedy for a very long time;
  • Blood sugar and insulin levels are maintained at the required level;
  • Promotes the rejection of sweet products and diet;
  • Helps to get rid of excess weight.


  • To get a positive effect, you will have to take it for at least 10 days.


3. Glycostabil

Glycostabil photo

In third place in our ranking of the best blood sugar lowering drugs is a hypoclemic type drug based on the latest generation of a sulfonylurea derivative. It has a direct effect on carbohydrate metabolism, promotes the establishment of blood microcirculation in the tissues of the internal organs, as well as in the muscles. With its regular use, the right amount of insulin in the pancreas begins to be produced. Peripheral tissues become more sensitive to this hormone. From the moment of eating until the production of insulin, a minimum amount of time passes.

Hyperkleemia is reduced, and platelet adhesion and aggregation are also reduced. The medicine does not allow the occurrence and progression of parietal thrombosis, restores vascular permeability, and prevents the development of atherosclerosis and microthrombosis. Even with an increased dosage, it does not lead to an increase in body weight, and in people already suffering from this disease, weight begins to decrease, especially if they strictly follow the diet prescribed to them. In the blood, the concentration of total cholesterol decreases. It is not permissible to take people under the age of 18, pregnant and lactating women, is contraindicated in the elderly.


  • A fairly effective drug that quickly lowers blood sugar and cholesterol levels, bringing them to normal levels;
  • Allows you to reduce body weight, provided that you follow the prescribed diet;
  • Improves the metabolism of carbohydrates, prevents the absorption of excess sugar into the blood.


  • The drug has a number of rather serious contraindications and side effects;
  • It consists exclusively of chemically synthesized compounds, not a single natural substance has been found here.


2. Glucophage Long

Glucophage Long photo

The main active substance here is metformin hydrochloride, which is accompanied by carmellose sodium, hypromellose and magnesium stearate. The drug is produced in the form of biconvex capsules, which are painted white or almost white. Metmorphine is a specially synthesized substance that keeps the amount of glucose in the blood plasma under full control. It is not responsible for the production of insulin, so even regular intake of this drug does not lead to hypoklemia. However, this medicine allows you to increase the sensitivity of receptors to insulin, therefore, the glucose contained in the blood is processed by the cells of the body as quickly as possible. In addition, the drug inhibits the production of glucose by the liver, does not allow it to be absorbed in the intestine.

After taking one tablet, the positive effect of this drug will last for almost 10 hours. The active substance is distributed throughout the body as evenly as possible, does not participate in metabolism, therefore it is excreted through the kidneys unchanged. However, this drug is only suitable for patients who do not have impaired renal function. It can be successfully combined with a large number of other drugs that are prescribed to patients with diabetes.


  • Helps to reduce excess weight;
  • It is successfully combined with a variety of drugs prescribed for diabetes;
  • Possesses long term of positive action;
  • Easy to take;
  • High concentration of active substances.


  • There are a number of contraindications and side effects.

Glucophage Long

1. Subetta

subetta photo

It has an active effect on the insulin receptor, due to which the sensitivity to the enzyme that the patient’s body produces on its own increases. The drug significantly increases glucose metabolism, helps to reduce the concentration of sugar in the blood, which, in combination with other drugs, provides complex therapy for such a dangerous disease as diabetes mellitus. In addition, the tool improves blood microcirculation. Due to this, more oxygen enters the cells, metabolism is accelerated, the walls of blood vessels are strengthened, but at the same time they become much more elastic. The drug is also characterized by a mild anti-anxiety effect. Subetta promotes the production of adiponectin. This is a special hormone that is produced by fat cells, because of it, the production of glucose by an organ such as the liver is reduced.

Take this remedy one tablet at a time. It should not be swallowed, chewed or washed down. The medicine is placed in the mouth and kept there until completely dissolved. The main active agent here are antibodies to the C-terminal concentrate of the insulin receptor, which pass through several levels of pharmacological purification. Additional compounds of the drug are isomalt, magnesium stearate and crospovidone. This drug is intended even for people with type 1 diabetes, but only as an adjunct to insulin therapy. There are practically no contraindications for the drug — it cannot be taken by people under the age of 18 and patients who have individual intolerance to individual components.


  • A very effective drug;
  • Acceptable cost;
  • The drug is indicated even for patients with type 1 diabetes;
  • Successfully combined with other drugs;
  • The minimum number of contraindications and side effects.


  • Not detected.


In conclusion, a useful video

So our rating of the best drugs for lowering blood sugar is coming to an end. I would like to express the hope that you have managed to choose the most suitable product for yourself or your loved ones among the products presented in the review in 2022. However, do not forget that with diabetes it is strictly forbidden to self-medicate — before purchasing the medicine you like, be sure to consult your doctor.


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